Circular RNA Encoding Yamanaka Factors Enables Partial Reprogramming Without Pluripotency
At the high level, exposing a cell to the Yamanaka factors first does nothing, then later rejuvenates epigenetic control over nuclear DNA structure and gene expression, and then later still causes the cell to dedifferentiate into an induced pluripotent stem cell. Much of the challenge in building re
<p>At the high level, exposing a cell to the Yamanaka factors first does nothing, then later rejuvenates epigenetic control over nuclear DNA structure and gene expression, and then later still causes the cell to dedifferentiate into an induced pluripotent stem cell. Much of the challenge in building re</p>