PD-L1 Blockade in the Brain Restores Measures of Glial Cell Function
PD-L1 found on the surface of cells is a well known immune checkpoint protein. When it binds to the receptor PD-1 found on the surface of T cells and B cells, it acts to suppress immune activity. This is a necessary brake to avoid runaway immune reactions, but because it is also abused by cancer cel
<p>PD-L1 found on the surface of cells is a well known immune checkpoint protein. When it binds to the receptor PD-1 found on the surface of T cells and B cells, it acts to suppress immune activity. This is a necessary brake to avoid runaway immune reactions, but because it is also abused by cancer cel</p>